This study discusses that the grammar of prayer healing in the Epistle of James has stronger characteristics of the middle voice than the passive voice. It reveals that prayer is related to inherent grace, that is, the cultivation of body, mind, and spirit, rather than the supernatural work of God. Therefore, it is emphasized that the church community must form a culture of prayer while complying with inherent grace or natural laws. Furthermore, this paper also suggests ways to practice God's healing depending on the type of disease. In particular, it emphasizes the holistic nature of healing where both prayer and medical treatment are playing their roles in the process of God’s healing practice. It appeals that prayer can play a role in the process of healing and make the people’s life healthier when the church community secures the holistic nature of God’s healing, but it can be served as a temptation to restrict people or replace their natural life when the holistic nature of healing is lost.